Four PIAA tournament games will take place there, beginning with a Friday night Class AA girls' doubleheader involving Delone Catholic and York Catholic.
The Fighting Irish (25-2) will take on Parkway Center of District 12 in the second game at 7:30 p.m. Parkway Center (9-4) lost its district consolation game and is the fourth-place team from that tournament.
The Irish, coming off their District 3 championship win against Delone, will follow the Squirettes (19-6), who play District 2 runner-up Scranton Holy Cross (19-7) at 6 p.m.
Saturday night will shift to the boys' Class AAAA first-round matchup for William Penn. The Bearcats (26-3), coming off their 78-76 district title loss in overtime to Harrisburg, will face Methacton (22-5), which finished seventh in District 1 - home to powers Chester, the No. 1-ranked team in the state, and Lower Merion.
After a heartbreaking loss to the Cougars on Saturday, William Penn coach Troy Sowers told his players he liked their potential matchups in the tournament.
Harrisburg and J.P. McCaskey were third and fourth in the last state poll. William Penn was fourth.
The earliest the Bearcats could see either of those teams is McCaskey in the quarterfinals, which would require both teams to win twice. Harrisburg sits on the other side of the bracket.
As for potential District 3 rematches, one will take place at 5 p.m. Saturday in Dallastown. Just like they did Saturday at Giant Center, the Susquehannock girls will take the floor before the Bearcats.
This time the District 3 Class AAA runners up will face Lancaster Catholic (25-1), a team it beat in the district quarterfinals at Milton-Hershey. The game was the Crusaders' only loss this season.
"Yeah we were just talking about that," Susquehannock coach Dave Schreiner said outside of his team's locker room Saturday following a 46-30 loss to Palmyra. "Lucky us, huh?
"I told the kids it wasn't a fluke the first time we beat them, and we're going to have to turn around and do it again."
The most YAIAA teams in any classification is triple-A girls with the Warriors, West York and Eastern York. Also, soon-to-be league member Gettysburg qualified for the tournament.
West York will travel to Norristown Area High School at 4:30 p.m. Saturday to meet District 1 champion Villa Maria Academy, while Eastern takes on Prep Charter at 5 p.m. the same day at South Philadelphia High School.
The lone Class AAAA girls' team to qualify is Dover, which will take on West Chester Rustin at 6 p.m. Friday in Norristown.
As for the remaining boys' teams: New Hope Academy in Class A takes on School at Church Farm at 5 p.m. Friday at Plymouth-Whitemarsh; Delone Catholic will drive to Northern York to face Wellsboro Area at 5 p.m.; and Northeastern in Class AAA gets District 11 champion Allentown Central Catholic on Friday at Freedom High school in Bethlehem. That game tips off at 7:30 p.m.